Humanized monoclonal antibodies against human interleukin-5

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

4241301, 4241331, 4241411, 4241581, 435 691, 435 696, 435 7021, 435326, 435335, 435346, 5303871, 5303873, 5303881, 53038823, 536 231, 536 234, 536 2353, 536 235, A61K 39395, C07K 1624, C12N 1513, C12N 512

Patent

active

060569573

ABSTRACT:
A monoclonal antibody is provided which specifically binds to human interleukin-5. Also provided are a hybridoma which produces the monoclonal antibody; complementary DNAs which encode the heavy and light chain variable regions of the monoclonal antibody and CDRs therefrom; humanized monoclonal antibodies; and pharmaceutical compositions comprising the monoclonal antibody or anti-idiotypic antibodies directed against it, humanized monoclonal antibodies, binding fragments, binding compositions or single-chain binding proteins derived from the antibody and a physiologically acceptable carrier.

REFERENCES:
patent: 5091513 (1992-02-01), Huston et al.
patent: 5096704 (1992-03-01), Coffman et al.
patent: 5530101 (1996-06-01), Queen et al.
Blood 77: xxxiii-xxxv (1991) Information For Contributor.
Denburg, J. A. et al. Blood 77: 1462-1468, Apr. 1991.
Queen, C. et al. Proc. Natl. Acad. Sci. USA 86: 10029-10033, Dec. 1989.
Riechmann, L. et al. Nature 332: 323-327, Mar. 1988.
Brennan et al., Science 229:81 (1985).
Denburg et al., Blood 77(7):1462 (1991).
Geysen et al., J. Immunol. Meth. 102:259 (1987).
Jameson et al., Nature 341:465 (1989).
Kabat et al., Sequences of Proteins of Immunological Interest, 4th Edition, 1987, U.S. Dept. of Health & Human Services, National Institutes of Health.
Kohler and Milstein, Eur. J. Immunol. 6:511 (1976).
Larrick et al., Bio/Technology 7:934 (1989).
Lewis et al., Gene 101(2):297 (1991).
Liu et al., Proc. Natl. Acad. Sci. USA 84:3439 (1987).
Milstein, Immunology Recognition and Response, 1991, W.E. Paul, Ed. W.H. Freedman & Company, New York, pp. 124-134.
Miyajima et al., TIBS 17:378 (1992).
Queen et al., Proc. Natl. Acad. Sci. USA 86:10029 (1989).
Regenmortel, Immunogenicity of Protein Antigens: Repertoire and Regulation, 1987, E. Sercarz and J. Borzofsky, Eds., CRC Press, Inc., Boca Raton, Florida, pp. 21-28.
Riechmann et al., Nature 332:323 (1988).
Saiki et al., Science 239:487 (1988).
Saragovi et al., Science 253:792 (1991).
Schmitter et al., Mol. Immunol. 27:1029 (1990).
Shulman et al., Nature 276:269 (1978).
Tavernier et al., DNA 8(7):491 (1989).
Zurawksi et al., EMBO J. 8:2583 (1989).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Humanized monoclonal antibodies against human interleukin-5 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Humanized monoclonal antibodies against human interleukin-5, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Humanized monoclonal antibodies against human interleukin-5 will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1591941

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.