Humanized antibody against S-surface antigen of hepatitis B...

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...

Reexamination Certificate

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Reexamination Certificate

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07435414

ABSTRACT:
A humanized antibody of the present invention shows similar antigen-binding affinity to a mouse monoclonal antibody and significantly low immunogenecity. Therefore, the humanized antibody of the present invention can be effectively used for treating chronic hepatitis B and preventing HBV infection of a patient received liver transplantation and vertical transmission from a mother infected with HBV to a fetus.

REFERENCES:
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patent: 6924368 (2005-08-01), Lee et al.
patent: 7112664 (2006-09-01), Lee et al.
patent: WO 01/92529 (2001-12-01), None
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Korean Patent Abstracts of Korean Patent Laid-Open Publication No. 10-2004-12266 published Feb. 11, 2004.
Korean Patent Abstracts of Korean Patent Laid-Open Publication No. 10-2004-12267 published Feb. 11, 2004.

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