Humanized antibodies to human gp39, compositions containing ther

Details Humanized antibodies to human gp39, compositions containing ther Humanized antibodies to human gp39, compositions containing ther

1995-11-07

1999-12-14

Chan, Christina Y.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

4241301, 4241331, 4241441, 4241431, 4241531, 4241541, 4241731, 4241411, 5303871, 5303873, 5303881, 5303882, 53038822, 5303887, 53038873, 53038875, 536 2353, A61K 39395, C07K 1628

Patent

active

060013583

ABSTRACT:
The present invention is directed to humanized antibodies which bind human gp39 and their use as therapeutic agents. These humanized antibodies are especially useful for treatment of autoimmune diseases.

REFERENCES:
patent: 5474771 (1995-12-01), Lederman et al.
Durie, F., et al, "Prevention of Collagen-Induced Arthritis with an Antibody to gp39, the Ligand for CD40." Science, vol. 261, No. 5126 (Sep. 3, 1993), pp. 1328-1330.

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