Humanized antibodies to human gp39, compositions containing ther

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

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4241301, 4241331, 4241441, 4241431, 4241531, 4241541, 4241731, 4241411, 5303871, 5303873, 5303881, 5303882, 53038822, 5303887, 53038873, 53038875, 536 2353, A61K 39395, C07K 1628

Patent

active

060013583

ABSTRACT:
The present invention is directed to humanized antibodies which bind human gp39 and their use as therapeutic agents. These humanized antibodies are especially useful for treatment of autoimmune diseases.

REFERENCES:
patent: 5474771 (1995-12-01), Lederman et al.
Durie, F., et al, "Prevention of Collagen-Induced Arthritis with an Antibody to gp39, the Ligand for CD40." Science, vol. 261, No. 5126 (Sep. 3, 1993), pp. 1328-1330.

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