Humanized antibodies against human 4-1BB

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007910, C435S007920, C436S514000, C436S547000, C436S015000, C530S387500, C530S387100, C530S388200

Reexamination Certificate

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06887673

ABSTRACT:
A humanized antibody that binds to human 4-1BB and that allows binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating cancer in a subject comprising administering a therapeutically effective amount of the antibody to said subject.

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