Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1997-11-20
2000-03-14
Saunders, David
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
53038875, 5303911, 5303913, 5303917, 536 2353, 4353201, C12P 2108, C07H 2104, C12N 1513
Patent
active
060374543
ABSTRACT:
Humanized anti-CD11a antibodies and various uses therefor are disclosed. The humanized anti-CD11a antibody may bind specifically to human CD11a I-domain, have an IC50(nM) value of no more than about 1 nM for preventing adhesion of Jurkat cells to normal human epidermal keratinocytes expressing ICAM-1, and/or an IC50 (nM) value of no more than about 1 nM in the mixed lymphocyte response assay.
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Jardieu Paula M.
Presta Leonard G.
Genentech Inc.
Lee Wendy M.
Saunders David
Schwartz Timothy R.
VanderVegt F. Pierre
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