Humanized anti-amyloid beta antibodies

Details Humanized anti-amyloid beta antibodies Humanized anti-amyloid beta antibodies

2011-04-26

2011-04-26

Kolker, Daniel E (Department: 1649)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Structurally-modified antibody, immunoglobulin, or fragment...

C424S139100, C424S141100, C424S152100, C530S387300, C530S388100

Reexamination Certificate

active

07931899

ABSTRACT:
Humanized anti-Aβ antibodies derived from a murine antibody directed to a N-terminal epitope of Aβ are described. The humanized antibodies have reduced or no human T cell epitopes and bind Aβ with an affinity similar to that of the murine antibody.

REFERENCES:
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patent: WO 2007/050359 (2007-05-01), None
patent: WO 2007/064972 (2007-06-01), None
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PCT Search Report and Written Opinion dated Nov. 4, 2009.

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