Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2006-08-08
2006-08-08
Huff, Sheela (Department: 1643)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S005000, C435S235100, C435S320100, C530S387300, C530S388100, C530S388230, C536S023530
Reexamination Certificate
active
07087409
ABSTRACT:
A humanized murine antibody is provided. The amino acid sequences of a light chain complementarity determining region from a mouse antibody are grafted onto a human light chain, and a heavy chain complementarity determining region from a mouse antibody are grafted onto a human antibody heavy chain to produce libraries from which a humanized murine antibody having the desired specificity is selected.
REFERENCES:
patent: 5565332 (1996-10-01), Hoogenboom et al.
patent: 5859205 (1999-01-01), Adair et al.
Paul, Fundamental Immunology, Raven Press, NY, Chapter 8, p. 242, 1993.
Brooks et al J. Clin. Invest. 96:1815-1822, 1995.
Rader et al. Proc. Natl. Acad. Sci. USA, 95:8910-8915, Jul. 1998.
Barbas, III Carlos F.
Rader Christoph
Blanchard David J.
Huff Sheela
Olson & Hierl Ltd.
The Scripps Research Institute
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