Human β-adrenergic receptor kinase nucleic acid molecule

Details Human β-adrenergic receptor kinase nucleic acid molecule Human β-adrenergic receptor kinase nucleic acid molecule

2004-03-24

2010-11-09

Mondesi, Robert B (Department: 1652)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S320100, C435S252300, C435S071100

Reexamination Certificate

active

07829682

ABSTRACT:
Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.

REFERENCES:
patent: WO0153312 (2001-07-01), None
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N—Geneseq—200812 database AC AAI58393 from WO200153312 Jul. 26, 2001 Tang et al. Alignment with SEQ ID No. 56.
N—Geneseq—200812 database AC AAI58393 from WO200153312 Jul. 26, 2001 Tang et al. Alignment with SEQ ID No. 13.
Hanks Sk, Quinn Am., Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. Methods Enzymol. 1991;200:38-62.
Iaccarino et al, Myocardial overexpression of GRK3 in transgenic mice: evidence for in vivo selectivity of GRKs. Am J Physiol. Oct. 1998;275(4 Pt 2):H1298-306.
Peppel et al, G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization. J Biol Chem. Oct. 10, 1997;272(41):25425-8.
GenEmbl database Accession No. E03080 Shimotoono et al., Sep. 29, 1997 from JP 1991201994. Alignment SEQ ID No. 1.
Sigma, Inc., Biochemicals and Reagents for Life Science Research. Catalogue, 1997, p. 1159.

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