Human voltage gated sodium channel β1A subunit and...

Details Human voltage gated sodium channel β1A subunit and... Human voltage gated sodium channel β1A subunit and...

2006-03-08

2008-08-05

Ulm, John (Department: 1649)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Reexamination Certificate

active

07408036

ABSTRACT:
DNAs encoding human voltage gated sodium channel β1A subunit have been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.

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