Human virus causing severe acute respiratory syndrome (SARS)...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S023720

Reexamination Certificate

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07375202

ABSTRACT:
The present invention relates to an isolated novel virus causing Severe Acute Respiratory Syndrome (SARS) in humans (“hSARS virus”). The hSARS virus is identified to be morphologically and phylogenetically similar to known member of Coronaviridae. The present invention provides the complete genomic sequence of the hSARS virus. Furthermore, the invention provides the nucleic acids and peptides encoded by and/or derived from the hSARS virus and their use in diagnostic methods and therapeutic methods, including vaccines. In addition, the invention provides chimeric or recombinant viruses encoded by said nucleotide sequences and antibodies immunospecific to the polypeptides encoded by the nucleotide sequences.

REFERENCES:
patent: 2003/0224353 (2003-12-01), Stein et al.
Genbank Accession No. AY274119, “SARS Coronavirus Tor2, complete genome,” version AY274119.1, Apr. 14, 2003.
SARS-associated Coronavirus. Genomic Sequence Availability. [online] [retrieved on Jul. 21, 2005]. Retreived from the Internet <URL: http://www.bcgsc.ca/bioinfo/SARS>.
Genbank Accession No. AY278491, “SARS Coronavirus,” verison AY278491.1, Aug. 29, 2003.
Sharma et al (Bioinformatics 20:1074-1080, May 1, 2004).
Zhi et al. SARS Vaccine: Progress and Challenge, Cellular & Molecular Immunology, Apr. 2005, vol. 2, No. 2, p. 101-105.
Navas-Martin et al. Coronavirus replication and pathogenesis: Implications for the recent outbreak of severe acute respiratory syndrome (SARS), and the challenge for vaccine development. Journal of NeuroVirology, 2004, vol. 10, p. 75-85.
Jiang et al. SARS Vaccine Development, Emerging Infectious Diseases • www.cdc.gov • Jul. 2005, vol. 11, No. 7, p. 1016-1020.
Reimann, H.A., 1974, ‘Chest Cold’ or Viral Pneumonia? How to Tell the Difference,Asian J. Mod. Med., 10(11): 412-416.
Stephensen, C.B., Apr. 1999, Phylogenetic Analysis of a Highly Conserved Region of the Polymerase Gene From 11 Coronaviruses and Development of a Consensus Polymerase Chain Reaction Assay,Virus Research, 60(2): 181-189.
Demirkiran, O. et al., Apr. 2003, Severe Acute Respiratory Syndrome,Sendrom, 15(4): 88-95.
Kulichenko, A.N., 2003, Severe Acute Respiratory Syndrome (SARS). Peculiarities of Laboratory Diagnostics,Problemy Osobo Opasnykh Infektsii, (85): 164-170.
Ruan, Y., May 2003, Comparative Full-Length Genome Sequence Analysis of 14 SARS Coronavirus Isolates and Common Mutations Associated with Putative Origins of Infection,Lancet, 361(9371): 1779-1785.
Marra, Marco A., May 2003, The Genome Sequence of the SARS-Associated Coronavirus,Science300(5624): 1399-1404.
Rota, P.A., May 2003, Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome,Science300(5624): 1394-1399.
Qin, E. et al., May 2003, A Complete Sequence and Comparative Analysis of a SARS-Associated Virus,Chinese Science Bulletin, 48(10): 941-948.
Wang, Y. et al., May 2003, Immunoinformatic Analysis for the Epitopes on SARS Virus Surface Protein,Journal of Peking University, 35 Suppl: 70-71.
Thiel, V. et al., Sep. 2003, Mechanisms and Enzymes Involved in SARS Coronavirus Genome Expression,Journal of General Virology, 84(9): 2305-2315.
Shi, R. et al., Jun. 2003, Design and Application of 60mer Oligonucleotide Microarray in SARS Coronavirus Detection,Chinese Science Bulletin, 48(12): 1165-1169.
Li, G. et al., 2003, Development of the Specific Antibodies Against Coronavirus in 20 Patients with Sars,Zhongguo Mianyixue Zazhi, 19(16): 372-374.
Li, D. et al., 2003, Novel Coronavirus Sequences Found in SARS Patients' Tissues and Sera,Chinese J. of Virology, 19(2): 97-99.
Bi, S. et al., Aug. 2003, Complete Genome Sequences of the SARS-CoV: the BJ Group,Genomics, Proteomes & Bioinformatics, 1(3): 180-192.
Odynets, K.A., Sep.-Oct. 2003, Molecular Aspects of Organization and Expression of SARS-CoV Coronavirus Genome,Biopolimery I Kletka, vol. 19, No. 5, pp. 414-431.
Zhu R. et al., Sep. 2003, SARS-Associated Coronavirus Gene Fragments Were Detected From a Suspected Pediatric SARS Patient,Chinese Journal of Pediatrics, 41(9): 641-4.
Chim, S.S.C. et al., Nov. 2003, Genomic Characterization of the Severe Acute Respiratory Syndrome Coronavirus of Amoy Gardens Outbreak in Hong Kong,Lancet, 362(9398): 1807-1808.

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