Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2004-07-21
2009-06-30
Peng, Bo (Department: 1648)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S320100, C530S333000, C530S333000
Reexamination Certificate
active
07553944
ABSTRACT:
The present invention provides the complete genomic sequence of a novel human coronavirus, coined as coronavirus-HKU1 (“CoV-HKU1”), isolated in Hong Kong from a patient who had a recent history of visit to Schenzhen, China. The virus belongs to the order Nidovirales of the family Coronaviridae, being a single-stranded RNA virus of positive polarity. The invention also provides the deduced amino acid sequences of the complete genome of the CoV-HKU1. The nucleotide sequences and deduced amino acid sequences of the CoV-HKU1 are useful in preventing, diagnosing and/or treating the infection by CoV-HKU1. Furthermore, the invention provides immunogenic and vaccine preparations using recombinant and chimeric forms as well as subunits of the CoV-HKU1 based on the nucleotide sequences and deduced amino acid sequences of the CoV-HKU1.
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Zhao P. et al “DNA vaccine of SARS-Cov S gene induces antibody response in mice”. Acta Biochim Biophys Sin (Shanghai). Jan. 2004;36(1):37-41. See marked p. 1-4.
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Chan Kwok Hung
Guan Yi
Lau Kar Pui Susanna
Peiris Joseph Sriyal Malik
Poon Lit Man
Peng Bo
Saliwanchik Lloyd & Saliwanchik
The University of Hong Kong
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