Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1997-01-23
1999-04-06
Huff, Sheela
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 723, 530324, 530350, C07H 2104, G01N 33574, A61K 3800, C07K 100
Patent
active
058920161
ABSTRACT:
The present invention provides a novel human tumor suppressor (NHTS) and polynucleotides which identify and encode NHTS. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NHTS and a method for producing NHTS. The invention also provides for agonists, antibodies, or antagonists specifically binding NHTS, and their use, in the prevention and treatment of diseases associated with expression of NHTS. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding NHTS for the a treatment of diseases associated with the expression of NHTS. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding NHTS.
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Brie Sam La
Goli Surya K.
Billings Lucy J.
Eyler Yvonne
Huff Sheela
Incyte Pharmaceuticals
Mohan-Peterson Sheela
LandOfFree
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