Human tumor necrosis factor polypeptides

Details Human tumor necrosis factor polypeptides Human tumor necrosis factor polypeptides

1993-07-01

1994-02-22

Draper, Garnette D.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Lymphokines, e.g., interferons, interlukins, etc.

530395, 930144, 424 851, 435 695, 435 697, C07K 1300, A61K 3702

Patent

active

052888525

ABSTRACT:
A novel cloned DNA encoding a human tumor necrosis factor (TNF), a vector having said DNA inserted thereinto, a host transformed with said vector and a novel human TNF polypeptide, and processes for producing them.

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Pennica et al., Nature, vol. 312 Dec. 20-27, 1984, pp. 724-728.
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Shirai et al., Nature, vol. 313, pp. 803-806 (Feb., 1985).
Williamson et al Proc Natl Acad Sci. vol. 80 (17) pp. 5171-5174 Sep. 1983 "Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin".

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