Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-04-16
1998-04-14
Elliott, George C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435243, 4353201, 435325, 435410, 536 231, 536 235, C12P 2106, C12N 510, C12N 1512, C12N 1563
Patent
active
057390100
ABSTRACT:
The present invention provides a human transcription factor (HTRAN) and polynucleotides which identify and encode HTRAN. The invention also provides expression vectors and host cells, agonists, antibodies, or antagonists. The invention provides methods for treating diseases associated with expression of HTRAN.
REFERENCES:
Crossley et al, Molecular and Cellular Biology, vol. 16(4): pp. 1695-1705, Apr. 1996.
Perkins, A., et al., "Lethal .beta.-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF," Nature, 375:318-322 (1995).
Pritchard-Jones, K., et al., "The candidate Wilm's tumour gene is involved in genitourinary development," Nature, 346:194-197 (1990).
Kreidberg, J., et al., "WT-1 is Required for Early Kidney Development," Cell, 74:679-691 (1993).
Orkin, S. (GI 1244514; GI 1244515) GenBank Sequence Database (Accession U36340), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894.
Sogawa, K., et al., "cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2," Nucleic Acids Research, 21(7):1527-1532 (1993) (GI 303596; GI 303597).
Hillman Jennifer L.
Shah Purvi
Billings Lucy J.
Elliott George C.
Incyte Pharmaceuticals Inc.
McKelvey Terry A.
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