Human tissue plasminogen activator

Details Human tissue plasminogen activator Human tissue plasminogen activator

1995-06-06

1998-05-19

Jacobson, Dian C.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435212, 4352402, 424 9464, C12N 950, C12N 964, C12N 1555, A61K 3849

Patent

active

057534861

ABSTRACT:
A human tissue plasminogen activator (t-PA) is produced in useful quantities using recombinant DNA techniques. The invention disclosed thus enables the production of t-PA free of contaminants with which it is ordinarily associated in its native cellular environment. Methods, expression vehicles and various host cells useful in its production are also disclosed.

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