Human tissue plasminogen activator

Details Human tissue plasminogen activator Human tissue plasminogen activator

1995-06-06

1997-12-30

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

536 232, C12N 950, C12N 1558

Patent

active

057029385

ABSTRACT:
Human tissue plasminogen activator (t-PA) is produced in useful quantities using recombinant DNA techniques. The invention disclosed thus enables the production of t-PA free of contaminants with which it is ordinarily associated in its native cellular environment. Methods, expression vehicles and various host cells useful in its production are also disclosed.

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