Human tissue plasminogen activator

Details Human tissue plasminogen activator Human tissue plasminogen activator

1988-04-21

1989-08-01

Huleatt, Jayme A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435212, 4352402, 43525233, 935 14, 935 70, 935 73, C12N 964, C12N 948, C12N 500, C12N 120, C12N 1500

Patent

active

048533300

ABSTRACT:
Human tissue plasminogen activator (t-PA) is produced in useful quantities using recombinant DNA techniques. The invention disclosed thus enables the production of t-PA free of contaminants with which it is ordinarily associated in its native cellular environment. Methods, expression vehicles and various host cells useful in its production are also disclosed.

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