Human T cell hybridomas which produce immunosuppressive factors

Details Human T cell hybridomas which produce immunosuppressive factors Human T cell hybridomas which produce immunosuppressive factors

1984-06-28

1987-05-12

Hazel, Blondel

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435 68, 4351722, 435948, 935101, 530380, C12N 500, C12N 1500, C12R 191

Patent

active

046650326

ABSTRACT:
A human T cell hybridoma comprising the product of:

REFERENCES:
patent: 4544632 (1985-10-01), Yamamura et al.
Irigoyen et al., "Generation of Functional Human T Cell Hybrids", J. Exp. Med., vol. 154, 1981, pp. 1827-1837.
Grillot-Courvalin et al., "Establishment of a Human T-Cell Hybrid Line with Suppressive Activity", Nature, vol. 292, Aug. 27, 1981, pp. 844 and 845.
Laurence, J., "The Immune System in AIDS", Scientific American, vol. 253, No. 6, Dec. 1985, pp. 84-93.
Laurence, J. et al., "Immunoregulatory Lymphokines of T Hybridomas from AIDS Patients: Constitutive and Inducible Suppressor Factors", Science, vol. 225, Jul. 6, 1984, pp. 66-68.
Laurence, J. et al., "Lymphadenopathy-Associated Viral Antibody in AIDS", The New England Journal of Medicine, V. 311, N. 20, Nov. 15, 1984, pp. 1269-1273.
Joller-Jemelka, H. I. et al., "Immunologishe Laboruntersuchungen bei Patienten mit Erworbenem Immunmangelsyndrom (AIDS) und bei AIDS-Verdacht", Schweiz. med. Wschr., V. 115, (1985), pp. 125-132.
Laurence, J. et al, "Soluble Suppressor Factors in Patients with AIDS . . . ", J. Clin. Invest., vol. 72, pp. 2072-2081, 1983.
Shohat, B. et al., "Serum Suppressor Factor in Patients with AIDS . . . ", First Annual. Conf. Medical Research, Petah Tikva, Israel, May 23, 1984.
Greene, W., "Production of Human Suppressor T Cell Hybridomas", J. of Immunology, vol. 129, No. 5, pp. 1986-1992, 1982.
Grillot-Courvalin et al, "Establishment of Human T-Cell Hybrid Line with Suppressive Activity", Nature, vol. 292, pp. 844-845, 1981.

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