Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-02
1999-11-30
Ulm, John
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 697, 435325, 435243, 4353201, 536 231, 536 234, 536 2351, C12N 1512, C12N 1563, C12N 121, C12N 500
Patent
active
059941030
ABSTRACT:
A human stanniocalcin-alpha polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for the treatment of electrolyte disorders which lead to renal, bone and heart diseases and osteoporosis and Paget's Disease. Antagonists against such polypeptides and their use therapeutically to treat hypocalcemia and osteoporosis are also disclosed. Use of the stanniocalcin-alpha sequence as a diagnostic to detect diseases or the susceptibility to diseases related to a mutated form of stanniocalcin-alpha seqeunces is also disclosed.
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Stern, P. H., et al., Journal of Bone and Mineral Research, 6(11):1153-1159 (1991).
Fleischmann Robert D.
Olsen Henrik S.
Hoover Kenley K.
Human Genome Science, Inc.
Saoud Christine
Ulm John
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