Human serine protease gene

Details Human serine protease gene Human serine protease gene

1986-12-31

1990-11-27

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435 691, 435 701, 435 711, 435 91, 4351721, 4351723, 4352402, 4352523, 435320, 435212, 435213, 536 27, 935 6, 935 9, 935 14, 935 18, 935 22, 935 60, 935 72, C12N 964, C12N 948, C12N 1552, C12N 121, C12N 510, C12N 1570, C12N 1574, C12N 1579

Patent

active

049735551

ABSTRACT:
Novel human serine proteases are provided characterized by expression in cytotoxic killer cells, being about 25.8kD, and having the amino acid residues of the serine protease charge-relay catalytic mechanism conserved. The proteases can be produced by recombinant DNA technology. The cDNA is also provided.

REFERENCES:
patent: 4783410 (1988-11-01), Pasternack et al.
Lobe et al., Biochemistry, vol. 27, #18, 6942-6948 (1988).
Pasternack et al., Nature, vol. 314 (1985), 743-746.
Lobe et al., Proc. Natl. Acad. Sci., vol. 83 (1986), 1448-1452.

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