Human semaphorin L (H-SemaL) and corresponding semaphorins...

Details Human semaphorin L (H-SemaL) and corresponding semaphorins... Human semaphorin L (H-SemaL) and corresponding semaphorins...

2008-03-04

2008-03-04

Borin, Michael (Department: 1631)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C514S002600

Reexamination Certificate

active

10933746

ABSTRACT:
The invention relates to novel semaphorins which are distinguished by a particular domain structure and derivatives thereof, nucleic acids (DNA, RNA, cDNA) which code for these semaphorins, and derivatives thereof, and the use thereof.The present invention relates to semaphorins which have a novel, as yet undisclosed and unexpected domain structure and which possess a biochemical function in the immune system (immunomodulating semaphorins). The novel semaphorins are referred to as type L semaphorins (SemaL). They comprise an N-terminal signal peptide, a characteristic Sema domain and, in the C-terminal region of the protein, an immunoglobulin-like domain and a hydrophobic domain which represents a potential transmembrane domain.

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