Human rotaviruses, vaccines and methods

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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4242151, 4242051, 435236, A61K 3915, A61K 3912, C12N 704

Patent

active

056957670

ABSTRACT:
A Novel isolated human rotavirus is disclosed. The novel human rotavirus of the present invention has derived its genomic segments from parental strains of different genogroups and/or serotypes, and is designated as HRV 248. It has been deposited with the American Type Culture Collection (ATCC), 12301 Parklawn Drive, Rockville, Md. 20852, and has been assigned the ATCC accession no. VR 2274. Also disclosed are novel vaccines formulated with the human rotaviruses of the present invention, and methods of vaccinating humans against human rotaviruses of multiple serotypes with such vaccines.

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