Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2007-01-02
2007-01-02
Myers, Carla J. (Department: 1634)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S023100, C536S024300, C536S024310, C435S320100, C435S252300
Reexamination Certificate
active
10396678
ABSTRACT:
An isolated nucleic acid containing a human ribonucleotide reductase M2 subunit promoter sequence or genomic sequence. Also disclosed are methods of determining whether a subject is suffering from or at risk for developing a cell proliferation-associated disorder, identifying a compound for treating a cell proliferation-associated disorder, treating a cell proliferation-associated disorder, and developing a procedure for treating a cell proliferation-associated disorder.
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Jae B. Park et al. “Characterization of the Promoter of the Human Ribonucleotide Reductase R2 Gene”. Biochemical and Biophysical Research Communications 264:651-657, 2000.
B. Zhou et al. “Characterization of the human ribonucleotide reductase M2 subunit gene; genomic structure and promoter analyses”. Cytogenet. Cell. Genet. 95:52-59, 2001.
B. Zhou et al. “Human ribonucleotide reducatase M2 subunit gene amplification and transcriptional regulation in a homogeneous staining chromosome region responsible for the mechanism of drug resistance”. Cytogenet. Cell. Genet. 95:34-42, 2001.
Fish & Richardson P.C.
Myers Carla J.
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