Human Rgr oncogene and truncated transcripts thereof...

Details Human Rgr oncogene and truncated transcripts thereof... Human Rgr oncogene and truncated transcripts thereof...

2008-05-20

2008-05-20

Harris, Alana M. (Department: 1643)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S320100, C435S069100, C536S023500

Reexamination Certificate

active

10625471

ABSTRACT:
Naturally-occurring variants of human Rgr oncogene protein, in particular, abnormally truncated variants found in T cell malignancies, as well as the human Rgr protein are encompassed by the present invention. Also included are antibodies thereto and nucleic acid molecules encoding human Rgr protein and naturally-occurring variants thereof. The present invention further provides methods for diagnosing and treating T cell malignancies associated with abnormally truncated transcripts of human rgr oncogene and/or abnormal truncation of human Rgr protein.

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