Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease
Patent
1998-02-12
2000-08-29
Achutamurthy, Ponnathapu
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Transferase other than ribonuclease
435 691, 435 697, 4352523, 4353201, 435 6, 435 15, 536 232, 536 235, C12N 910, C12N 120, C12N 1500, C12P 2106, C07H 2104
Patent
active
061107174
ABSTRACT:
The hRCE1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing hRCE1 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
REFERENCES:
Sequence Comparison between Accession No. W96411 and SEQ ID No. : 1 (result 9), Jul. 16, 1996.
Sequence Comparison between Matsubara Sequence and SEQ ID No. : 1 (result 10), Feb. 11, 1995.
Chen et al. "Solubilization, Partial Purification, and Affinity Labeling of the Membrane-Bound Isoprenylated Protein Endoprotease", Biochemistry, vol. 35, pp. 3227-3237 (1996).
Akopyan et al. "Proteolytic Processing of Farnesylated Peptides: Assay and Partial Purification From Pig Brain Membranes of an Endopeptidase which has the Characteristics of E.C.", Biochemical and Biophysical Research Communications, vol. 198 (2), pp. 787-794 (1994).
Nishi et al. "Partial Purification and Characterization of CAAX-Motif-Specific Protease from Bovine Brain Using a Novel Pluorometric Assay", Journal of Biochemistry, vol. 122, pp. 402-408 (1997).
EMBL Database, Accession No. W96411, Jul. 16, 1996.
EMBL Database, Accession No. AA168614, Dec. 19, 1996.
EMBL Database, Accession No. W14344, Apr. 26, 1996.
EMBL Database, Accession No. AA021859, Jan. 26, 1997.
EMBL Database, Accession No. AA470901, Jun. 28, 1997.
Swissprot Accession #Q03530.
Boyartchuk, V.L. et al., "Modulation of Ras and a-Factor Function by Carboxyl-Terminal Proteolysis", Science, vol. 275, pp. 1796-1800 (1997).
Kikly Kristine Kay
Knab Anne M
Southan Christopher Donald
Achutamurthy Ponnathapu
Hecht Elizabeth J.
King William T.
Saidha Tekchand
SmithKline Beecham Corporation
LandOfFree
Human RCE1 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Human RCE1, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human RCE1 will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1248740