Human proteins kinases

Details Human proteins kinases Human proteins kinases

1998-07-07

2000-04-04

Nashed, Nashaat

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Transferases

435194, 43525233, 4353201, 536 232, C12N 912, A61K 3845

Patent

active

060457929

ABSTRACT:
The present invention provides novel human protein kinases (HPK) and polynucleotides which identify and encode HPK. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPK. The invention also provides for pharmaceutical compositions comprising HPK or antagonists of HPK, and antibodies which specifically bind HPK. Additionally, the invention provides antisense molecules to HPK for treatment or prevention of diseases associated with abnormal expression of HPK.

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Webster, M.K., et al., "Characterization of sgk, a Novel Member of the Serine/Threonine Protein Kinase Gene Family Which Is Transcriptionally Induced by Glucocorticoids and Serum" Mol. and Cell Biol., 13:2031-2040 (1993).
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