Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Reexamination Certificate
2005-04-19
2005-04-19
Martinell, James (Department: 1631)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
C530S350000, C435S069100, C514S012200
Reexamination Certificate
active
06881823
ABSTRACT:
The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
REFERENCES:
patent: WO 0073454 (2000-12-01), None
patent: WO 0168848 (2001-09-01), None
GenBank Accession No. NM006811, Bossolasco et al., “Homo sapienstumor differentially expressed 1 (TCE1), mRNA” (Jul. 20, 1999).
GenBank Accession No. Z97053, Ho, S., “Human DNA sequence from clone RP1-179M20 on chromosome 20 Contains a 3′ end of a novel gene similar to cellular retinaldehyde-binding protein, the TDE1 gene (Tumour differentially expressed 1), the PKIG gene Encoding protein kinase (cAMP-dependent, catalytic) inhibitor gamma, the 3′ end of the ADA gene encoding adenosine deaminase, a putative novel gene, 2 CpG islands, ESTs, STSs and GSSs, complete sequence” (Apr. 9, 2001).
GenBank Accession No. AF164794, Gu et al.,Homo sapiensDiff33 protein homolog mRNA, complete cds (Jul. 2, 1999).
GenBank Accession No. U49188, Dakour et al., “Human placenta (Diff33) mRNA, complete cds” (Feb. 14, 1996).
Swissport Locus Q13530, Bossolasco et al., Tumor differentially expressed protein 1 (Transmembrane protein SBBI99) (Jul. 20, 1999).
Nimmrich et al., “Seven genes that are differentially transcribed in colorectal tumor cell lines,”Cancer Letters160 (1):37-43 (Nov. 10, 2000).
Hu et al., “Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning,”PNAS97(17):9543-9548 (Aug. 15, 2000).
Bossolasco et al., “The HumanTGEGene Hemologue: Localization to 20q13.1-13.3 and Variable Expression in Human Tumor Cell Lines and Tissue,”Molec. Carcinogenesis26:189-200 (1999).
GenBank Accession No. AL137261, Koehrer et al., “Homo sapiensmRNA; cDNA DKFZp434H0413 (from clone DKFZp434H0413); partial cds” (Feb. 18, 2000).
GenBank Accession No. BC033029, Strausberg, R.,Homo sapiens, KIAA1253 protein, clone MGC:33018 IMAGE:4831122, mRNA, complete cds (Jun. 24, 2002).
Florence Charles
Rosen Craig A.
Ruben Steven M.
Human Genome Sciences Inc.
Human Genome Sciences Inc.
Martinell James
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