Human prohibitin DNA

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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536 235, 43525231, 43525233, 43525421, C07H 2104, C12N 1585

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055997074

ABSTRACT:
A human prohibitin gene, a protein coded for by said gene, a gene analysis reagent to be used with them, and a quantitative determination of prohibitin in a biological sample by an immunological technique with the use of an antihuman prohibitin antibody and a method for analyzing a prohibitin gene of a human tissue for the occurrence of mutation by the PCR method with the use of oligonucleotides having partial base sequences of said gene as primers.

REFERENCES:
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Malkin et al., Science 250, 1233-1238 (1990).
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Franklin et al., J. Cell. Biochem. suppl. 17D, 159(Abst 0-310) (1993).
Sato et al., Cancer Research 52, 1643-1646 (Mar. 16, 1992).
Adams et al., Nature 355, 632-634 (Feb. 13, 1992).
Nuell et al, Mol. Cell. Biol. 11(3), 1372-1381 (Mar. 1991).
Lundwell, Bioch. Biophys. Res. Comm. 161(3), 1151-1159 (1989).
White et al., Genomics 11, 228-230 (1991).

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