Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2005-11-01
2005-11-01
Kemmerer, Elizabeth (Department: 1646)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C435S069100
Reexamination Certificate
active
06960649
ABSTRACT:
Novel human Kv4.3 polypeptides, polynucleotides which encode these polypeptides, and methods for producing these polypeptides are provided. Diagnostic, therapeutic, and screening methods employing the polynucleotides and polypeptides of the present invention are also provided.
REFERENCES:
patent: 6368823 (2002-04-01), Bril et al.
Dixon et al. Roel of the Kv4.3 K+ channel in ventricular muscle—A molecular correlate for the transient outward current. Circ Res. Oct., 1996, 79(4):659-68.
Locus KCD3_RAT, and P70622, Dixon et al., Circ Res. 1996, 79(4):659-68 (sequence search results only).
Serodio, E., et al., “Cloning of a Novel Component of A-Type K+ Channels Operating at Subthreshold Potentials with Unique Expression in Heart and Brain.”Journal of Neurophysiology, 75(5):2174-2179 (1996).
Dixon, J., et al., “Role of the Kv4.3 K+ Channel in Ventricular Muscle,”Circulation Research, 79(4): 659-668 (1996).
Dilks, O., et al., “Cloning and Expression of the Human Kv4.3 Potassium Channel,”Rapid Communication, 1974-1977 (1998).
Ohya, S., et al., “Molecular Cloning and Tissue Distribution of an Alternatively Spliced Variant of an A-Type K+ Channel α-subunit, Kv4.3 in the Rat,”FEBS Letters, 420: 47-53(1997).
Isbrandt, Dirk, et al., Gene Structures and Expression Profiles of Three Human KCND (Kv4) Potassium Channels Mediating A-Type Current /TOand /SA,Genomics64, Dec. 21, 1999, pp. 144-154.
Cockett Mark Ian
Dilks Daniel Wayne
Ling Huai-Ping Chang
Sokol Patricia Tyson
Dyke Raymond Van
Jiang Dong
Kemmerer Elizabeth
Wyeth
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