Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-05
1998-01-20
Walsh, Stephen
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352402, 4352523, 435325, 435530, 435350, 435536, 435 235, C12P 2102, C12N 1512, C07K 14705
Patent
active
057100195
ABSTRACT:
Disclosed are human K.sub.+ channel polypeptides and DNA (RNA) encoding such K.sub.+ channel polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques. Agonists for such K.sub.+ channel polypeptides are also disclosed. Such agonists may be used to treat epilepsy, stroke, hypertension, asthma, Parkinson's disease, schizophrenia, anxiety, depression and neurodegeneration. Also disclosed are antagonists against such polypeptides which may be used to treat AIDS, SLE, diabetes, multiple sclerosis and cancer. Also disclosed are diagnostic assays for detecting mutations in the polynucleotide sequences of the present invention.
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Adams Mark D.
Li Yi
White Owen R.
Busham Daryl A.
Human Genome Sciences Inc.
Mullins J. G.
Olstein Elliot M.
Walsh Stephen
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