Human plasminogen activator variants having amino acids 37-42 su

Details Human plasminogen activator variants having amino acids 37-42 su Human plasminogen activator variants having amino acids 37-42 su

1992-04-16

1995-04-18

Hill, Jr., Robert J.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435212, 4352402, 4353201, 536 232, C12N 500, C12N 1500, C12N 1558, A61K 37547

Patent

active

054078199

ABSTRACT:
A TPA variant with replacement of amino acids is provided. In a typical embodiment, the variant has an amino acid sequence with replacement of the amino acid group consisting of asparagine at the 37th position, serine at the 38th position, glycine at the 39th position, arginine at the 40th position, alanine at the 41st position, and glutamine at the 42nd position from the N-terminus of the amino acid sequence of mature human tissue plasminogen activator.

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