Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2006-08-08
2006-08-08
Fredman, Jeffrey (Department: 1637)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S006120
Reexamination Certificate
active
07087734
ABSTRACT:
This invention relates to novel nucleic acid sequences encoding three novel human phosphodiesterase (hPDE IV) isozymes. It also relates to polypeptides encoded by such sequences.This invention also relates to an assay method for detecting the presence of such novel isozymes in human cells, and to a method of identifying compounds or other substances that inhibit or modify the activity of such isozymes.
REFERENCES:
patent: 5527896 (1996-06-01), Wigler et al.
patent: 5631286 (1997-05-01), Christensen, IV et al.
patent: 6323041 (2001-11-01), Fisher et al.
patent: 6489457 (2002-12-01), Fisher et al.
Davis et al., Proc. Natl. Acad. Sci (USA), May 1989, 86: 3604-3608.
Kurihara et al., Biochem. Biophys. Res. Comm, Aug. 1990, 170(3): 1074-1081.
Livi et al., Mol. Cell Biol., Jun. 1990, 10(6): 2678-2686.
Torphy et al., J. Biol. Chem., Jan. 1992, 267(3): 1798-1804.
McLaughlin et al., J. Biol. Chem. 268(9): 6470-6476.
McHale et all, Molecular Pharmacology, 39: 109-113.
Fisher Douglas A.
Robbins Michael D.
Benson Gregg C.
Fredman Jeffrey
Pfizer Inc.
Slepchuk Nicholas I.
LandOfFree
Human phosphodiesterase IV isozymes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Human phosphodiesterase IV isozymes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human phosphodiesterase IV isozymes will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3631001