Human PEN11B-related gene variant associated with lung cancers

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C536S023100

Reexamination Certificate

active

07108973

ABSTRACT:
The invention relates to a novel human PEN11B-related gene variant, and to the use of the nucleic acid of the gene variant in diagnosing diseases, in particular, lung cancer, e.g. small cell lung cancer.

REFERENCES:
patent: WO 9738131 (1997-10-01), None
“On the preparation and utilization of isolated and purified oligonucleotides” [electronic resource], Andrew Chin, allegedly deposited in UNC library on Mar. 14, 2002, date of publication, if any, is in question.
Sethi, T. “Science, medicine, and the future: Lung cancer”BMJ, 314(7081): 652, (1997).
Kondo, M., et al. “Selective maternal-allele loss in human lung cancers of the maternally expressed p57KIP2gene at 11p15.5”Oncogene, vol. 12, p. 1365-1368, (1996).
Xu, X.L, et al. “Inactivation of Human SRBC, Located within the 11p15.5-p15.4 Tumor Suppressor Region, in Breast and Lung Cancers”Cancer Research, vol. 61, p. 7943-7949, (2001).

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