Human p51 genes and gene products thereof

Details Human p51 genes and gene products thereof Human p51 genes and gene products thereof

2006-11-07

2006-11-07

Yu, Misook (Department: 1642)

Chemistry: molecular biology and microbiology

Vector, per se

C435S070100, C435S325000, C435S069100, C536S023100

Reexamination Certificate

active

07132276

ABSTRACT:
Novel human genes falling whithin the category of family genes relating to p53 gene which is known as a cell proliferation regulatory gene, and gene products thereof. A human p51 gene characterized by containing a base sequence encoding an amino acid sequence represented by SEQ ID NO:1; a human p51 gene having a base sequence consisting of the 145- to 1488-bases in the sequence represented by SEQ ID NO:2; vectors containing these genes; host cells transformed with these vectors; a process for producing a p51 protein having the amino sequence represented by SEQ ID NO:1; which comprises culturing the above host cells and harvesting the protein from the thus obtained culture; and the p51 protein having the amino acid sequence represented by SEQ ID NO:1.

REFERENCES:
patent: 97/28186 (1997-08-01), None
patent: WO 97/28186 (1997-08-01), None
patent: WO 98/51350 (1998-11-01), None
patent: WO 99/19357 (1999-04-01), None
patent: WO 99/47674 (1999-09-01), None
patent: WO 99/50287 (1999-10-01), None
patent: WO 99/61610 (1999-12-01), None
Yang, et al., Sep. 1998, Mol. Cell, 2:305-316.
Osada, et al., Jul. 1998, Nat. Med. 4(7):839-843.
Fu, et al., 1995, Proc. Natl. Acad. Sci. vol. 92:10162-66.
GenEmbi accession No. Y11414 (Sep. 2, 1997).
Chan et al (1993, Proc. Natl. Acad. Sci. USA. vol. 90, pp. 11371-11375).
Gene vol. 112 No. 2 (1992) C. Caron de Fromentel er al., “Rainbow trout p53: cDNA cloning and biochemical characterization” p. 241-245.
A. Yang, et al., “p63, a p53 Homolog at 3q27-29,, Econdes Multiple Products with Transactivating, Death-Inducing, and Dominant-Negative Activities”, Molecular Cell, vol. 2, 305-316, Sep. 1998.
M. Senoo, et al., “A Second p53-Related Protein, P73L, with High Homology to p731”, Biochemical and Biophysical Research Communications 248, 603-607 (1998), Article No. RC989013.
M. Kaghad, et al., “Monoallelically Expressed Gene Related to p53 at Ip36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers”, Cell, vol. 90, 809-819, Aug. 22, 1997.
M. Osada, et al., “Cloning and functional analysis of human p51, with structurally and functionally resembles p53”, Nature Medicine, vol. 4, No. 7, pp. 839-843, Jul. 1998.
M. Kato, et al., “Upregulation of the Elongation Factor 1α Gene by p53 in Association With Death of an Erythroleukemic Cell Line”, Blood, vol. 90, (Aug. 15), 1997, pp. 1373-1378.
X. Xu et al., “A Mouse Erythroleukemia Cell Line Possessing Friend Spleen Focus-forming Virus gp55 Transgene and Temperature-sensitive Mutant p53 Gene”, Jpn. J. Cancer Res., 86, 284-291, Mar. 1995.
C. Caron de Fromentel, et al., “Rainbow trout p53: cDNA cloning and biochemical charaterization”, Gene, 112 (1992) 241-245.
International Search Report.
Schmale and Bamberger. A novel protein with strong homology to the tumor suppressor p53.Oncogene15:1363-1367 (1997).
Harlow et al,Molecular and Cellular Biology, 5(7):1601-1610 (1985).

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