Human osteoclast derived cathepsin

Details Human osteoclast derived cathepsin Human osteoclast derived cathepsin

2007-06-26

2007-06-26

Belyavskyi, Michail (Department: 1644)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C530S388100, C530S389100, C530S391100

Reexamination Certificate

active

11185877

ABSTRACT:
Disclosed is a human osteoclast-derived cathepsin (Cathepsin O) polypeptide and DNA(RNA) encoding such cathepsin O polypeptides. Also provided is a procedure for producing such polypeptide by recombinant techniques. The present invention also discloses antibodies, antagonists and inhibitors of such polypeptide which may be used to prevent the action of such polypeptide and therefore may be used therapeutically to treat bone diseases such as osteoporosis and cancers, such as tumor metastases.

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