Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-09-19
2006-09-19
O'Hara, Eileen B. (Department: 1646)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S325000, C435S069100, C435S320100, C530S350000, C536S023500
Reexamination Certificate
active
07108991
ABSTRACT:
The invention disclosed in this patent document relates to transmembrane receptors, more particularly to endogenous, human orphan G protein-coupled receptors.
REFERENCES:
patent: 5462856 (1995-10-01), Lerner et al.
patent: 5514578 (1996-05-01), Hogness et al.
patent: 5532157 (1996-07-01), Fink
patent: 5573944 (1996-11-01), Kirschner et al.
patent: 5639616 (1997-06-01), Liao et al.
patent: 5750353 (1998-05-01), Kopin et al.
patent: 6051386 (2000-04-01), Lerner et al.
patent: 6221660 (2001-04-01), Bonini et al.
patent: 6468756 (2002-10-01), Bonini et al.
patent: 6555344 (2003-04-01), Matsumoto et al.
patent: 2003/0064381 (2003-04-01), Feder et al.
patent: 2003/0125539 (2003-07-01), Bonini et al.
patent: 2003/0180813 (2003-09-01), Ohishi et al.
patent: 2135253 (1996-05-01), None
patent: 0 860 502 (1998-08-01), None
patent: 0 899 332 (1999-03-01), None
patent: 0 913 471 (1999-05-01), None
patent: 0 913 471 (1999-05-01), None
patent: 1 092 727 (2001-04-01), None
patent: WO 99/24569 (1999-05-01), None
patent: WO 97/11159 (1996-09-01), None
patent: WO 97 20045 (1997-06-01), None
patent: WO 97/21731 (1997-06-01), None
patent: WO 97 24929 (1997-07-01), None
patent: WO98/00552 (1998-01-01), None
patent: WO 98 31810 (1998-07-01), None
patent: WO98/34948 (1998-08-01), None
patent: WO98/38217 (1998-09-01), None
patent: WO 98 39441 (1998-09-01), None
patent: WO98/46995 (1998-10-01), None
patent: WO 98 50549 (1998-11-01), None
patent: WO 99 55732 (1999-04-01), None
patent: WO 99 24463 (1999-05-01), None
patent: WO 99 25830 (1999-05-01), None
patent: WO 99 42484 (1999-08-01), None
patent: WO 99 46378 (1999-09-01), None
patent: WO99/52927 (1999-10-01), None
patent: WO 99 52945 (1999-10-01), None
patent: WO 99/55733 (1999-11-01), None
patent: WO99/55733 (1999-11-01), None
patent: WO 99 55734 (1999-11-01), None
patent: WO99/64436 (1999-12-01), None
patent: WO 00 11015 (2000-03-01), None
patent: WO 00 11166 (2000-03-01), None
patent: WO 00 11170 (2000-03-01), None
patent: WO 00 12707 (2000-03-01), None
patent: WO00/22131 (2000-04-01), None
patent: WO 00 23588 (2000-04-01), None
patent: WO 00 26369 (2000-05-01), None
patent: WO 00 28028 (2000-05-01), None
patent: WO 00/31258 (2000-06-01), None
patent: WO00/50562 (2000-08-01), None
patent: WO 01/32864 (2001-05-01), None
patent: WO 01/36473 (2001-05-01), None
patent: WO01/42288 (2001-06-01), None
patent: WO 01/87929 (2001-11-01), None
patent: WO 02/16548 (2002-02-01), None
patent: WO02/44362 (2002-06-01), None
patent: WO02/064789 (2002-08-01), None
Fehmann et al., End. Rev. 16: 390-410, 1995.
Feighner, et al., “Receptor for Motilin Identified in the Human Gastrointestinal System,” Science, American Association for the Advancement of Science, U.S., vol. 284, No. 5423, Jun. 25, 1999, pp. 2164-2188.
Karen Kulju McKee, et al., “Cloning and Characterization of Two Human G Protein-Coupled Receptor Genes (GPR38 and GPR39) Related to the Growth Hormone Secretagogue and Neurotensin Receptors,” Genomics, Academic Press, San Diego, U.S., vol. 46, No. 3, 1997, pp. 423-434.
Lefkowitz, Robert J., et al., “Constitutive Activity of Receptors Coupled to Guanine Nucleotide Regulatory Proteins,” Trends in Pharmacological Sciences, vol. 14, No. 8, 1993, pp. 303-307.
Palyha, O.C., et al., “Ligand Activation Domain of Human Orphan Growth Hormone (GH) Secretagogue Receptor (GHS-R) Conserved from Pufferfish to Humans,” Molecular Endocrinology, Baltimore, MD., U.S., vol. 14, No. 1, Jan. 2000, pp. 160-169.
European Search Report dated Aug. 20, 2004.
Standaert and Young, Treatment of Central Nervous System Degenerative Disorders, Chapter 22, Section III, Drugs Acting on the Central Nervous System, in Goodman and Gilman's Pharmacological Basis of Therapeutics, 9th, ed. (1995) pp. 503-519.
Matsumoto, et al., “An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system,” Biochem. Biophys. Res. Comm. (2000) 272:576-582.
Bentley, “Genomic sequence information should be release immediately and freely to the public,” The Sanger Institute: Human Genome Project, Policy Forum, Science (1996) 274:533-534.
The Sanger Institute: Data Release Policy, www.sanger.ac.uk, May 24, 2002.
Genbank Acc. #AL035423, update version of Feb. 12, 1999.
Genbank Acc #AL035423, update version of Feb. 24, 1999.
Genbank Acc. #AL035423, update version of Feb. 27, 1999.
Genbank Acc. #AL035423, update version of Apr. 21, 1999.
Genbank Acc. #AL035423, update version of Nov. 23, 1999.
Sequence Revision History for Genbank Acc. #AL035423.
Johnson and Bressler, “New Pharmacologic Approaches”, Chap. 59 in Ellenberg and Rifkin's Diabetes Milletus, 5thed., Appleton and Lange, publishers, 1990, pp. 1293-1294.
Thorens, “Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1,” Proc. Natl. Acad. Sci. (1992) 89:8641-8645.
Thorens, “Glucagon-like peptide-1 and control of insulin secretion,” Diabete Metabolisme (1995) 21:311-318.
Volz, et al., “Molecular cloning, functional expression, and signal transduction of the GIP-reseptor cloned from a human insulinoma,” FEBS Lett. (1995) 373:23-29.
Bhathena, et al., “Insulin, glucagon and somatostatin secretion by cultured rat islet cell tumor and its clones,” Proc. Soc. Exptal. Biol. Med. (1984) 175:35-38.
ATCC database search on insulinoma.
ATCC database search on pancreas & beta cell.
ATCC No. CRL-2055 on NIT-1 cell line.
ATCC No. CRL-2057 on RIN-m cell line.
ATCC No. CRL-2058 on RIN-5F cell line.
ATCC No. CRL-2059 on RIN-14B cell line.
Shyrock, et al, “Inverse agonists and neutral antagonists of recombinant human A1 adenosine receptors stably expressed in Chinese hamster ovary cells,” Mol. Pharmacol. (1998) 53:886-893.
Wenzel-Seifert, et al., “High constitutive activity of the human formyl peptide receptor,” J. Biol. Chem. (1998) 273:24181-24189.
Forman, et al., “Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta,” Nature (1998) 395:612-615.
Seifert, et al., “Different effects of G alpha splice variants on beta2 adrenoreceptor-mediated signalling,” J. Biol. Chem. (1998) 273:5109-5116.
Bergsma, et al., “Cloning and characterization of a human anglotensin II type 1 receptor,” Biochem. Biophys. Res. Comm. (1992) 183:989-995.
Gantz, et al., “Molecular cloning, expression and gene localization of a fourth melanocortin receptor,” J. Biol. Chem. (1993) 268:15174-15178.
Groblewski, et al., “Mutation of asn111 in the third transmembrane domain of the AT1a angiotensin II receptor induces its constitutive activation,” J. Biol. Chem. (1997) 272:1822-1826.
Koike, et al., “Human type 2 angiotensin II receptor gene: cloned, mapped to the X chromosome, and its mRNA is expressed in the human lung,” Biochem. Biophys. Res. Comm. (1994) 203:1842-1850.
Kyaw, et al., “Cloning, characterization and mapping of human homolog of mouse T-cell death-associated gene,” DNA Cell Biol. (1998) 17:493-500.
Noda, et al., “The active state of the AT1 angiotensin receptor is generated by angiotensn II Induction,” Biochemistry (1996) 35:16435-16442.
Reppert, et al., “Cloning of a melatonin-related receptor from human pituitary,” FEBS Lett. (1996) 386:219-225.
Scheer, et al., “Constitutively active Gprotein-coupled receptors: potential mechanisms of receptor activation,” J. Receptor Signal Transduction Res. (1997) 17:57-73.
Bertin, et al, “Cellular signalling by an agonist-activated receptor/Gs-alpha protein,” Proc. Natl. Acad. Sci. USA (1994) 91:8827-8831.
Wise, et al., “Rescue of functional interactions between the alpha-2A adrenoreceptor and acylation-resistant forms of Gi1-aplha by expressing the proteins from chimeric open reading frames,” J. Biol. Chem. (1997) 272:24673-24678.
Burt, et al., “Agonist occupation of an alpha-2A-adre
Chen Ruoping
Leonard James N.
Arena Pharmaceuticals Inc.
Chandra Gyan
Dialynas Deno P.
O'Connor Cozen
O'Hara Eileen B.
LandOfFree
Human orphan G protein-coupled receptors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Human orphan G protein-coupled receptors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human orphan G protein-coupled receptors will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3583993