Human oligodendroglial progenitor cell line

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435368, 435392, 435402, C12Q 168, C12N 510

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active

058306510

ABSTRACT:
A human pre-oligodendroglial stem cell line, HOP-1, is provided herein. The cell line is useful for methods of treatment of central nervous system disorders, as well as for neuropharmaceutical drug discovery.

REFERENCES:
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Lubetzki et al. Gene Transfer of Rat Mature Oligodendrocytes and Glial Progenitor Cells with the LaxZ Gene. Ann. N.Y. Acad. Sci. 1990, vol. 605, pp. 66-70.
Tenebaum et al. Adeno-Associated Virus (AAV) as a Vector for Gene Transfer Into Glial Cells of the Human Central Nervous System. Gene Therapy. 1994, vol. 1, Suppl. 1, p. S80.
Noble et al. From Rodent Glial Precursor Cell to Human Glial Neoplasia in the Oligodendrocyte-Type-2 Astrocyte Lineage. Glia. 1995, vol. 15, pp. 222-230.
Kukekov et al. Characterization of a Perpetuated Human Oligodendroglial Progenitor Cell Culture. Society for Neuroscience Abstracts. 1995, vol. 21, pp. 319, abstract No. 134.3.
Espinosa et al. Oligodendroglial Progenitors Grafted in an Ectopic Location Migrate and Integrate in a histo type Manner in the Developing Rat Cerebellum. Journal of Neurochemistry. 1995, vol. 64, p. S29, abstract D

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