Human nucleotide pyrophosphohydrolase

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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536 235, 536 2431, 536 243, 4352523, 4353201, 435194, 435195, C07H 2104, C12N 1563, C12N 1585

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active

058769633

ABSTRACT:
The invention provides a human nucleotide pyrophosphohydrolase (NTPPH-1) and polynucleotides which identify and encode NTPPH-1. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of NTPPH-1.

REFERENCES:
Swan, A. et al., "Submicroscopic crystals in osteoarthritic synovial fluids" Ann.Rheum.Dis. (1994) 53:467-470.
Lohmander, L.S. et al., "Metalloproteinases, Tissue Inhibitor, and Proteoglycan Fragments in Knee Synovial Fluid in Human Osteoarthritis" Arthritis Rheum. (1993) 36:181-189.
Ryan, L.M. et al., "Adenosine Triphosphate Levels in Human Plasma" J.Rheumatol. (1996) 23:214-219.
Park, W. et al., "Inorganic Pyrophosphate Generation from Adenosine Triphosphate by Cell-Free Human Synovial Fluid" J.Rheumatol. (1996) 23:665-671.
Derfus, B.A. et al., "Articular Cartilage Vesicles Generate Calcium Pyrophosphate Dihydrate-Like Crystals In Vitro" Arthritis Rheum. (1992) 35:231-240.
Cardenal, A. et al., "Identification of a Nucleotide Pyrophosphohydrolase From Articular Tissues In Human Serum" Arthritis Rheum. (1996) 39:252-256.
Cardenal, A. et al., "Specificity of a Procine 127-KD Nucleotide Pyrophosphohydrolase for Articular Tissues" Arthritis Rheum. (1996) 39:245-251.
Hillier, L. et al., (GI 1515673), GenBank Sequence Database (Accession AA039396), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894.
Cottage, A. (GI 1070094) GenBank Sequence Database (Accession Z68011), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894. (GI 1070093).
Cottage, A. (GI 1070091), GenBank Sequence Database (Accession Z68011), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894. (GI 1070094).
Wilson, R. et al., "2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans" Nature (1994) 368:32-381. (GI 1070093; GI 1070094).

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