Human nucleic acid methylases

Details Human nucleic acid methylases Human nucleic acid methylases

1998-05-20

2000-08-01

Carlson, Karen Cochrane

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

4353201, 4352523, 435 6, 536 232, C12N 910, C12N 1500, C12N 120, C12Q 168, C07H 2104

Patent

active

060965266

ABSTRACT:
The invention provides a human nucleic acid methylases (HNAM) and polynucleotides which identify and encode HNAM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HNAM.

REFERENCES:
Hillier et al. EST database Accession No. W38874, May 1996.
Hillier et al. EST database Accession No. N42421, Jan. 1996.
Watson et al. Recombinant DNA, 2nd edition. pp. 106-107 and 453-455, 1992.
Accession No. T25530. Human gene signature HUMGS07700. Matsubara et al., Oct. 1996.
Accession No. AA452404. zx29d11.r1 Soares total fetus Nb2HF8 9w Homo sapiens cDNA clone 78793 5' similar to TR:G1209718. Hillier et al., Jun. 5, 1997.
Accession No. M74555. Mouse house-keeping protein mRNA, complete cds. Wang et al., Aug. 21, 1991.
Accession No. 42421. yy09f03.r1 Homo sapiens cDNA clone 270749 5' similar to PIR:S27870 house-keeping protein--mouse. Hillier et al., Jan. 25, 1996.
Lafontaine et al., "The DIM1 Gene Responsible for the Conserved m.sup.6.sub.2 AM.sup.6.sub.2 A Dimethylation in the 3'-Terminal Loop of 18 S rRNA is Essential in Yeast," J. Mol. Biol. (1994) 241, 492-497.
Graff et al., "Mapping Patterns of CpG Island Methylation in Normal and Neoplastic Cells Implicates Both Upstream and Downstream Regions in de Novo Methylation," J. Biol. Chem. (1997) 272, 22322-22329.
Baylin, et al., "Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia," Advances in Cancer Research, (1998) 141-196.
Gonzalgo and Jones, "Mutagenic and epigenetic effects of DNA methylation," Mutation Research (1997) 386, 107-118.
Tunny et al., "The Atrial Natriuretic Peptide Gene in Patients with Familial Primary Open-Angle Glaucoma," Biochemical and Biophysical Research Communications (1996) 223, 221-225.
Bokar et al., "Characterization and Partial Purification of MRNA N.sup.6 -Adenosine Methyltransferase from HeLa Cell Nuclei," J. Biol. Chem. (1994) 269, 17697-17704.

Affiliated with

Also associated with

Rating

Human nucleic acid methylases does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Human nucleic acid methylases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human nucleic acid methylases will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-662520