Human NPIK gene

Details Human NPIK gene Human NPIK gene

1998-04-07

1999-12-21

Degen, Nancy

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

530350, 536 235, C07H 2104, C07K 1447

Patent

active

060050888

ABSTRACT:
The present invention provides novel human genes, for example a novel human gene comprising a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO: 1. The use of the genes makes it possible to detect the expression of the same in various tissues, analyze their structures and functions, and produce the human proteins encoded by the genes by the technology of genetic engineering. Through these, it becomes possible to analyze the corresponding expression products, elucidate the pathology of diseases associated with the genes, for example hereditary diseases and cancer, and diagnose and treat such diseases.

REFERENCES:
Abstract of EMBO J., 12, pp. 339-347 (1993) for clone GEN-501D08.
GeneBank database accession D49738 for clone Gene-080G01.
GeneBank database accession Z4991, L34070, U18530 AND X59720 for clone Gen-025F07.
Abstract of Genomics, 9(4), pp. 728-736 (1991) for clone GEN-076C09.
Abstract of Nature, 357 (6380), pp. 700-702 (1992) for clone GEN-331G07.
GeneBank database accession Z19154 for clone GEN-163D09.
Abstract of Biochem. J., 297 (Pt2), pp. 389-397 (1994) for clone GEN-078D05.
Abstract of Mol. Gen. Genet., 244 (5), pp. 548-556 (1994) for clone GEN-432A12.
GeneBank database accession U19878 for clone GEN-092E10.
Abstract of Mol. Cell Biol., 15 (10), pp. 5645-5656 (1995) for clone GEN-4285B12.
Abstract of Genomics 22(2), pp. 425-430 (1994) for clone GEN-073E05.
Abstract of Dev. Dyn., 203 (2), pp. 212-222 (1995) for clone GEN-093E05.
Abstract of EMBO J., 8 (12), pp. 3807-3814 (1989 for clone GEN-077A09.
Hum. Genet., 86, pp. 14-16 (1990).
Proc. Natl. Acad. Sci., U.S.A., 87, pp. 6634-6638 (1990).
DNA Research, 2, 107-111 (1995).
Hum Genet., 88, pp. 119-121 (1991).
Peterson et al., "Identification of a Novel RaLGDS-Related Protein as a Candiate Effector for RAS and RAP1", J. Biol. Chem., 271(47):29903-29908, Nov. 1996.

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