Human neuronal nicotinic acetylcholine receptor compositions...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C530S350000

Reexamination Certificate

active

07119067

ABSTRACT:
Nucleic acid molecules encoding human neuronal nicotinic acetylcholine receptor alpha and beta subunits, mammalian and amphibian cells containing the nucleic acid molecules, and methods for producing alpha and beta subunits are provided. In particular, nucleic acid molecules encoding α6subunits and molecules encoding β3subunits of human neuronal nicotinic acetylcholine receptors are provided. In addition, combinations of a plurality of subunits, such as one or more of α1, α2, α3, α4, α5, α6and/or α7subunits in combination with one or more of β3subunits or such as one or more of β2, β3and/or β4subunits in combination with an α6subunit are provided.

REFERENCES:
patent: 5837489 (1998-11-01), Elliott et al.
Elliott et al.J. Mol. Neurosci., vol. 7, pp. 217-228, 1996, abstract only.
Gerzanich et al.Mol. Pharmacol., vol. 51, pp. 320-327, 1997, abstract only.
Grinevich et al.J PET, vol. 312, pp. 619-626, 2005, abstract only.
Quik et al.,Eur. J. Pharmacol., vol. 393, pp. 223-230, 2000, abstract only.
Quik et al.,J PET, vol. 316, pp. 481-489, 2006, abstract only.

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