Human neuronal cell line

Details Human neuronal cell line Human neuronal cell line

1991-04-25

1993-03-23

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

4352402, 43524021, C12Q 102, C12N 500

Patent

active

051963159

ABSTRACT:
This invention is directed to continuous, non-maligant, neuronal cell lines, the cells of which: a) in the undifferentiated form are essentially free of branched process; b) stain positively for neurofilament protein and neurotransmitters; c) do not stain positively for glial fibrillary acidic protein; and d) in the presence of nerve growth factor differentiate into cells with long branched processes. Derivative cell lines of such cell lines are also contemplated. The cell lines are useful in screening methods for evaluation of chemical and biological compounds as well as for therapeutic uses.

REFERENCES:
Ronnet et al, Science vol. 248, May 4, 1990, pp. 603-605.
Hirsch. Brain Research vol. 161 (1979) pp. 277-291.
Nye, et al., Neuroscience Abstracts, 14:92, 1988.
Guggino, et a., Neuroscience Abstracts, 15:996, 1989.
Dr. Lewis L. Judd, Statement for Public Health Service, 1990.
Dr. Frederick Goodwin, Statement for Public Health Serice.
Michael Specter, Washington Post, "Scientists Grow Brain Tissue in Laboratory", May 4, 1990, p. 1.
Borisy, et al., Society for Neuroscience Abstracts, 15:750, 1989.
Abstract of U.S. Ser. No. 07/487,894, filed Jun. 3, 1990.

Affiliated with

Also associated with

Rating

Human neuronal cell line does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Human neuronal cell line, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human neuronal cell line will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1350934