Human-murine hybridoma fusion partner

Details Human-murine hybridoma fusion partner Human-murine hybridoma fusion partner

1984-01-06

1987-01-06

Warren, Charles F.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

4351722, 435240, 435948, 435 5, 435 7, 424 11, 935 95, 935 96, 935100, 935103, 935106, 935110, 436548, C12N 500, C12N 1500

Patent

active

046346660

ABSTRACT:
By careful screening and mutation, a human-murine hybridoma suitable as a fusion partner for immortalizing an antibody-secreting B cell has been generated. The trioma fusion products of this immortalizing partner are stable producers of human monoclonal antibodies. A trioma which produces monoclonal human anti-varicella zoster is disclosed.

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