Human monoclonal antibody to lipid A of gram negative bacteria

Details Human monoclonal antibody to lipid A of gram negative bacteria Human monoclonal antibody to lipid A of gram negative bacteria

1993-08-25

1995-06-20

Lacey, David L.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

5303884, 5303882, 53038815, C12N 512, C07K 1612

Patent

active

054260469

ABSTRACT:
A human monoclonal antibody, C5, specific for lipid A of the endotoxin core of Gram-negative bacteria and the hybridoma cell line which produces the antibody. The monoclonal antibody is produced by the fusion of lipid A sensitized lymphocytes and an appropriate fusion partner.

REFERENCES:
patent: 5057598 (1991-10-01), Pollack et al.
Ziegler et al., The New England Journal of Medicine, vol. 307(20), pp. 1225-1230, Nov. 11, 1982.
Sevier, et al., Clin. Chem., 27(11):1797-1806, 1981.
Dunn et al., Surgery, 92:212-9, 1982.
Ziegler et al., Trans. Assoc. Amer. Phys., 91:253-8, 1978.
Waldmann, T. A., Science, 252:1657-1662, Jun. 21, 1991.
Spalding, B. J. , Bio technology, 11:428-429, Apr. 1993.
Sloan, A., The Washington Post, p. D3, Jan. 19, 1993.
Stone, R., Science, 259:1243, Feb. 26, 1993.
Wenzel, R. P., New England Journal of Med, 326(17):1151-1152, Apr. 23, 1992.
Warren et al., New Engl. Journal of Med, 326(17):1153-1157, Apr. 23, 1992.

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