Human monoclonal antibody to glycoprotein GPIII of varicella zos

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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5303883, C12N 528, C07K 1608

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active

056503199

ABSTRACT:
The human monoclonal antibody to the glycoprotein gpIII of varicella zoster virus (VZV), and hybridoma producing same, are provided. The hybridoma is obtained by immunizing human lymphocytes with gpIII antigen in the presence of a mitogen, and selecting a monoclonal antibody which reacts with a cell monolayer ELISA plate but substantially does not react with a cell homogenate ELISA plate.

REFERENCES:
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E. Montalvo et al. Virology 149:230-241, 1986.
Dubey et al. (1988) J. Infect. Diseases 157(5), 882-888.
Larussa et al. (1987) J. Clinic. Microbiol. 25(11), 2059-2062.

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