Human monoclonal antibody reactive with polyribosylribitol phosp

Details Human monoclonal antibody reactive with polyribosylribitol phosp Human monoclonal antibody reactive with polyribosylribitol phosp

1982-08-24

1988-05-17

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

4351722, 436548, 424 85, A61K 3940, C12N 1500, G01N 3353

Patent

active

047449829

ABSTRACT:
A human monoclonal antibody produced by a self-reproducing carrier cell, the antibody being reactive with PRP capsular polysaccharide. Also disclosed is a process of preparing the antibody from the carrier cell, which is conveniently a hybridoma. Additionally, diagnostic, prophylactic and therapeutic compositions and methods employing the antibody are disclosed. Moreover, a laboratory reagent containing the antibody is described.

REFERENCES:
patent: 4220717 (1980-09-01), Kuo
patent: 4407949 (1980-10-01), Kniskern et al.
Chemical Abstracts, vol. 98, Abstract No. 87354, 1983.

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