Human monoclonal antibody reactive with polyribosylribitol phosp

Details Human monoclonal antibody reactive with polyribosylribitol phosp Human monoclonal antibody reactive with polyribosylribitol phosp

1988-02-12

1990-09-04

Hazel, Blondel

Chemistry: molecular biology and microbiology

Spore forming or isolating process

530387, 424 858, 424 87, C12N 500, C07K 1500, C07K 1528

Patent

active

049544497

ABSTRACT:
A human monoclonal antibody produced by a self-reproducing carrier cell, antibody being reactive with PRP capsular polysaccharide. Also disclosed is a process of preparing the antibody from the carrier cell, which is conveniently a hybridoma. Additionally, diagnostic, prophylactic and therapeutic compositions and methods employing the antibody are disclosed. Moreover, a laboratory reagent containing the antibody is described.

REFERENCES:
patent: 4220717 (1980-09-01), Kuo
patent: 4407949 (1983-10-01), Kniskern et al.

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