Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1995-03-16
1998-04-28
Knode, Marian C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303888, 435 723, 435 724, 435 795, C07K 1630, G01N 33574, G01N 33577
Patent
active
057445850
ABSTRACT:
A human monoclonal antibody TB2A36C3 which shows high specificity against lung tumor antigens is described. TB2A36C3 can be used clinically for immunotherapy.
REFERENCES:
patent: 4585742 (1986-04-01), Bernal
patent: 4800155 (1989-01-01), Taniguchi et al.
patent: 5006470 (1991-04-01), Yamaguchi et al.
patent: 5134075 (1992-07-01), Hellstrom et al.
patent: 5227471 (1993-07-01), Wright, Jr.
patent: 5242824 (1993-09-01), Hellstrom et al.
patent: 5338661 (1994-08-01), Jensenius et al.
patent: 5348880 (1994-09-01), Hanna
Kusakabe, J. Nuclear Medicine, Feb. 1994 35:289-295.
Souhani, The Lancet, Aug. 8, 1987 pp. 325-326.
Illustrated Dictionary of Immunology, Cruse & Lewis, p. 107, 1995, CRC Press.
Derbyshire et al, Br. J. Cancer 67:1242-1247 (1993).
Cronin, Cancer Research 42:292-300, 1982.
Moore, Clin. Chem. 3519:1849-1853, 1989.
Souhani et al. JNCI 83:609-612, 1991.
Bhattacharya-Chatterjee, M. et al., 1990, "Murine Monoclonal Anti-idiotype Antibody as a Potential Network Antigen for Human Carcinoembryonic Antigen," J. of Immun., 145:2758-2765.
Brezicka, F.T. et al., 1991, "Tumor-Cell Killing by MAbs Against Fucosyl GM1, a Ganglioside Antigen Associated with Small-cell Lung Carcinoma," Int. J. Cancer, 49:911-918.
Caamano, J. et al., 1991, "Detection of p53 in Primary Lung Tumors and Nonsmall Cell Lung Carcinoma Cell Lines," Amer. J. Pathology, 139:839-845.
Chang, H.R. et al., 1994, "Tumor Associated Antigens Recognized by Human Monoclonal Antibodies," Ann. Surg. Oncol., 1(3):213-221.
Deng-Shun, W. et al., "Detection of Antigens Associated with Lung Carcinoma in Sera by Monoclonal Antibodies WLA-2C4 and Cl-3," Chinese Med. J., 105:905-908.
Denton, G.W.L., et al., 1994, "Clinical Outcome of Colorectal Cancer Patients Treated with Human Monoclonal Anti-Idiotypic Antibody," Int. J. Cancer, 57:10-14.
Ey, P.L. et al., 1978, "Isolation of Pure IgG.sub.1a, IgG.sub.2a and IgG.sub.2b Immunoglobulins from Mouse Using Protein A-Sepharose," Immunochemistry, 15:429-436.
Henderson, E. et al., 1977, "Efficiency of Transformation of Lymphocytes by EBV," Virology, 76:152-163.
Katsuki, T. et al., 1977, "Identification of the Target Cells in Human B Lymphocytes for Transformation by EBV," Virology, 83:287-294.
Lehmann, H.P. et al., 1992, "Tumor-Antigen-Specific Humoral Immune Response of Animals to Anti-Idiotypic Antibodies and Comparative Serological Analysis of Patients with Small-Cell Lung Carcinoma," Int. J. Cancer, 50:86-92.
Medcalf, E.A. et al., 1992, "Temperature-sensitive Mutants of p53 Associated with Human Carcinoma of the Lung," Oncogene, 7:71-76.
Moss, F. et al., 1991, "Differential Expression of Antigens by Human Small Cell Lunh Carcinoma in Sections of Tumour and in Serous Effusions," Br. J. Cancer, 63:54-55.
Niklinski J. et al., 1992, "Evaluation of Squamous Cell Carcinoma Antigen (SCC-Ag) in the Diagnosis and Follow-up of Patients with Non-small Cell Lung Carcinoma," Neoplasma, 39:279-282.
Pezzella, F., et al., 1993, "bcl-2 Protein in Non-small-cell Lung Carcinoma," NE J. of Medicine, 329:690-694.
Sanger, F. et al., 1977, "DNA Sequencing With Chain-terminating Inhibitors," PNAS, USA, 74:5463-5467.
Shijubo, N. et al., 1992, "Granulocyte Colony-Stimulating Factor-Producing Large Cell Undifferentiated Carcinoma of the Lung," Internal Medicine, 31:277-280).1.
Skov, B.G. et al., 1991, "Expression of `small cell carcinoma antigens` in Primary Small Cell Lunh Cancer and Metastases: an Immunohistochemical Study," Br. J. Cancer 63: 46-48.
Speirs, V. et al., 1993, "Localization of MOC-1 Cell Surface Antigen in Small-dell Lung Carcinoma Cell Lines: An Immunohistochemical and Immunoelectron Microscopic Study," J. Histochemistry & Cytochemistry, 41:1303-1310.
Stastny, J.J., et al., 1991, "Monoclonal Antibody Identification and Characterization of Two Human Sarcoma-associated Antigens," Cancer Research, 51:3768-3773.
Stephenson, J.R., et al., 1984, "Production and Purification of Murine Monoclonal Antibodies; Aberrant Elution from Protein A Sepharose CL-4b," Anal. Biochem., 142:189-195.
Underwood, P.A. et al, 1983, "Use of Protein A to Remove Immunoglobulins from Serum in Hybridoma Culture Media," J. Immunol. Methods, 60:33-45.
Waibel, R., et al., 1991, "Monoclonal Antibodies Defining the Cluster-5A Small Cell Lung Carcinoma Antigen," Br. J. Cancer, 63:29-32.
Yakose, T. et al., 1991, "Immunohistochemical and Ultrastructural Study of Mixed Small cell/Large cell Carcinoma of the Lung," Acta Pathol Jpn, 41:540-551.
Zwicky, C. et al., 1991, "Polyclonal Anti-idiotypic Antibodies Mimicking the Small Cell Lung Carcinoma Antigen Cluster 5A Interact with a Panel of Antibodies and Induce Specific Immune Response in Animals," Br. J. Cancer, 63:67-70.
Medenica Rajko D.
Mukerjee Sonjoy
Johnson Nancy A.
Knode Marian C.
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