Human monoclonal antibodies to herpes simplex virus and methods

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

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435 71, 53038815, 5303883, 5303873, 4241421, C07K 1608, A61K 39395, G01N 3353

Patent

active

061563137

ABSTRACT:
The present invention describes human monoclonal antibodies which immunoreact with Herpes simplex virus Type-1 and Type-2. Also disclosed are immunotherapeutic and diagnostic methods of using the monoclonal antibodies, as well as nucleic acids and cell lines for producing the monoclonal antibodies.

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Journal of General Virology 67, p. 1001 1986.
Cohen et al. Journal of Virology p. 102, 1984.
Barbas et al PNAS 88:7978 1991.
Hoogenboom et al. Nucleic Acids Research vol. 19 No. 15 4133 1991.
Seigneurin et al. Science vol. 221, 173 issued Jul. 8, 1983.

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