Human monoclonal anti-HIV-I-antibodies

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...

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4241421, 4241481, 435 7021, 4351722, 53038815, 53038835, 5303911, 5303917, C12N 524, C07K 1610, A61K 3942

Patent

active

057535035

ABSTRACT:
The invention is directed to human monoclonal antibodies specific for the gp41 envelope protein of human immunodeficiency virus type 1 (HIV-1). Specifically disclosed are the human monoclonal antibodies produced by the cell lines 3D6 having ECACC Accession No. 87110301, 24G3 having ECACC Accession No. 90091702 and 25C2 having ECACC Accession No. 80120601.

REFERENCES:
patent: 5087557 (1992-02-01), McClure
Fahey et al., "Status of Immune-based Therapies in HIV Infection and AIDS," Clin. Exp. Immunol. 88:1-5, 1992.
Fox, J.L., "No Winners Against AIDS," Bio/Technology 12:128, Feb. 1994.

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